- 1837: First admitted students
- 1888: College chartered
"From the Mt. Holyoke students one expects character of that high and beautiful type which Mary Lyon, the founder of this historic institution, so happily exemplified, together with thoroughness of achievement, unselfish devotion to duty, and love of the real and the true as distinguished from outward apperance alone." (Hemment 4).
"Constant supervision by teachers, rules governing the actions of every hour, and twice-daily periods of silent devotion characterized the disciplinary regime required of the first female collegians. Their seclusion and their enclosure within a single structure made such rigor possible." (Horowitz 4)